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Role and Mechanism of Secretory Autophagy Mediated by Vagus Nerve Electrical Stimulation in Achilles Tendinopathy

Role and Mechanism of Secretory Autophagy Mediated by Vagus Nerve Electrical Stimulation in Achilles Tendinopathy

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100044460
Enrollment
Unknown
Registered
2021-03-18
Start date
2021-04-08
Completion date
Unknown
Last updated
2021-09-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Achilles Tendinopathy

Interventions

Control group:conventional therapy
Treatment group:conventional therapy & vagus nerve electrical stimulation

Sponsors

Zhejiang Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1. Accord with the diagnostic criteria of orthopedics branch of American physiotherapists Association (2010 Edition) 2. Local Achilles tendon thickening with hypoechoic area and tendon fiber disorder confirmed by ultrasonography 3. Signed the informed consent.

Exclusion criteria

Exclusion criteria: 1) After Achilles tendon rupture or Achilles tendon rupture surgery; 2) Patients who have been treated by surgery, blocking or PRP injection; 3) Patients with autoimmune diseases and other infectious diseases; 4) Patients with gout; 5) Patients with tumor or other major systemic diseases; 6) Patients who do not cooperate or do not want to sign informed consent.

Design outcomes

Primary

MeasureTime frame
visual analogue scale;one-leg hopping test;victorian institute of sport assessment achilles questionnaire;—

Countries

China

Contacts

Public ContactWenjie Zhang

Zhejiang Provincial People's Hospital

287963464qq.com@qq.com+86 15990052629

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026