Hepatocellular carcinoma
Conditions
Interventions
single arm:Combined treatment with RFA and PD-1
Sponsors
The Fifth Medical Center of PLA General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Meet the clinical treatment standard of RFA; 2. Subjects volunteered to participate in this study, signed informed consent, good compliance, and cooperated with follow-up
Exclusion criteria
Exclusion criteria: 1. Severe jaundice, in large amount of ascites; 2. Extremely poor systemic condition or cachexia; 3. Severe liver insufficiency, Child-Pugh grade C; 4. Severe multiple organ dysfunction; 5. Active infection, especially combined with biliary infection; 6. Patients who had previously received embolization, liver radiotherapy or other ablative treatments; 7. The liver tumor burden was more than 70%, the main portal vein was completely blocked, and the upper gastrointestinal bleeding occurred within 1 month before enrollment. 8. Human immunodeficiency virus (HIV) infection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Relapse-free Survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| Progression Free Survival;Overall Survival;Object Response Rate;Disease Control Rate;Security; | — |
Countries
China
Contacts
Public ContactHui Xie
The Fifth Medical Center of PLA General Hospital
Outcome results
None listed