Laryngeal Edema
Conditions
Interventions
control group:underwent flexible bronchoscope and diagnosed laryngeal edema, received intravenous 20 mg methylprednisolone
experimental group:underwent flexible bronchoscope and diagnosed laryngeal edema, received epinephrine and budesonide sprayed on laryngeal edema through the bronchoscope
Sponsors
The First Affiliated Hospital of ZheJiang Chinese Medical University, Zhejiang Provincial Hospital of TCM
Eligibility
Sex/Gender
All
Age
16 Years to No maximum
Inclusion criteria
Inclusion criteria: Aged older than 16 years, duration of mechanical ventilation more than 24 h, and planned extubation during the stay in the ICU.
Exclusion criteria
Exclusion criteria: Pregnant, had a history of postextubation upper-airway obstruction presented with throat disease or surgery, had a tracheostomy, were chronically treated with non-steroidal anti-inflammatory drugs or corticosteroids, severe upper-airway bleeding, had already participated in this study, or were already included in another trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| laryngeal edema; | — |
Secondary
| Measure | Time frame |
|---|---|
| time between positive cuff leak test and extubation; | — |
Countries
China
Contacts
Public ContactRong-Lin Jiang
Department of ICU, The First Affiliated Hospital of ZheJiang Chinese Medical University, Zhejiang Provincial Hospital of TCM, Hangzhou, China
Outcome results
None listed