small for gestational age
Conditions
Interventions
Non catch-up growth:The guardian agrees and needs to use growth hormone therapy to give growth hormone therapy
catch-up growth:No
Sponsors
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
3 Years to 8 Years
Inclusion criteria
Inclusion criteria: 1. Children with SGA older than or equal to 3 years old and younger than 8 years old; 2. Have not used growth hormone therapy; 3. The guardian of the child is able to understand and is willing to participate in this study, and sign a written informed consent form.
Exclusion criteria
Exclusion criteria: 1. Use history of probiotics in the past month, including medicines and yogurt; 2. A history of antibiotic use in the past month; 3. A history of acute diarrhea in the past month; 4. People with severe congenital heart disease, gastrointestinal malformations, inflammatory bowel disease, liver and kidney damage, metabolic diseases, blood tumors, growth hormone deficiency.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| gut microbiota;Short-chain fatty acids;Biochemical indicators related to bone turnover; | — |
Countries
China
Contacts
Public ContactZhiya Dong
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed