Dry eye
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Subjects must be between 18 and 65 years of age; 2. Diagnosed as a dry eye patient by BUT and Schirmer I test; 3. Participants must agree to participate in the trial, and both guardians and subjects must sign written informed consent; 4. Patients who have sufficient time to complete the trial study.
Exclusion criteria
Exclusion criteria: 1. Patients with other co-morbidities of the eye that affect the determination of efficacy; 2. Patients with Sjgren's syndrome and other rheumatological diseases; 3. Patients with thyroid-related eye disease and other systemic diseases that affect dry eye conditions; 4. Patients with other significant systemic organic pathologies such as hypertension, diabetes mellitus and renal disease; 5. Patients with depression, obsessive-compulsive disorder and other mental abnormalities; 6. Patients with combined blepharospasm; 7. Pregnant and breastfeeding or planning a pregnancy; 8. Patients who are participating in other clinical trials; 9. Patients who are afraid of acupuncture or have contraindications to acupuncture such as blood clotting disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| OSDI;BUT;Tear inflammatory factors (TNF-alpha, IL-1 beta, NLRP3, MUC5AC); | — |
Secondary
| Measure | Time frame |
|---|---|
| Schirmer I test;CFS; | — |
Countries
China
Contacts
The Eye Hospital of Wenzhou Medical University