Multicenter clinical study on the role of brain injury markers in early diagnosis and prognosis evaluation of acute stroke

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100044379

Enrollment

Unknown

Registered

2021-03-17

Start date

2021-03-12

Completion date

Unknown

Last updated

2021-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

Gold Standard:The final clinical diagnosis as the gold standard is ischemic stroke, hemorrhagic stroke or stroke mimicry.

Index test:GFAP,&#32

PGP9.5,&#32

S100&#32

beta,&#32

NSE

Eligibility

Sex/Gender

All

Age

18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1) They have clinical symptoms of acute stroke; 2) Over 18 years old; 3) The onset time was within 6-12 hours;

Exclusion criteria

Exclusion criteria: 1) TBI history in recent 3 months; 2) He had a history of brain tumor, encephalitis, epilepsy and demyelinating disease of nervous system; 3) Pregnant and lactating women; 4) History of mental disorders and dementia; 5) Patients with shock after entering the room. 6) Accompanied by serious heart, lung, liver, kidney, blood system diseases. 7) Patients with severe infectious diseases.

Design outcomes

Primary

Measure	Time frame
SEN, SPE, ACC, AUC of ROC;	—

Countries

China

Contacts

Public ContactLi Xin

Guangdong Provincial People's Hospital

xlidoct@qq.com+86 18902233721

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026