Effect of Dexmedetomidine, Flurbiprofen Axetil and Their Combination on Post-Operative Sore Throat After Thyroidectomy

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100044376

Enrollment

Unknown

Registered

2021-03-17

Start date

2021-03-15

Completion date

Unknown

Last updated

2021-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-operative Sore Throat after Thyroidectomy

Interventions

Group NS:Normal Saline

Group D:Dexmedetomidine

Group F:Flurbiprofen Axetil

Group DF:Dexmedetomidine+Flurbiprofen Axetil

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients under general anesthesia for elective thyroidectomy, aged 18-65 years, no gender limitation, BMI 18-30 kg/m2, normal communication, and voluntary subjects signed informed consent were selected.

Exclusion criteria

Exclusion criteria: 1. Serious cardiopulmonary diseases; 2. history of mental diseases; 3. history of endocrine diseases; 4. history of hematological diseases; 5. history of reflux esophagitis; 6. history of tonsillar or vocal cord operations; 7. history of chronic pharyngitis; 8. history of perioperative long-term use of glucocorticoids.

Design outcomes

Primary

Measure	Time frame
post-operative sore throat;hoarseness;	—

Secondary

Measure	Time frame
Postoperative nausea and vomiting;	—

Countries

China

Contacts

Public ContactWeiwei Zhong

The First Affiliated Hospital of Anhui Medical University

zww.0511@hotmail.com+86 18214881269

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026