Central Serous Chrioretinopathy
Conditions
Interventions
1:Subthreshold micropulse laser
2:Spironolactone
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. aged >= 18 years; 2. Diagnosed with chronic CSC (>3 months); 3. The presence of subretinal fluid (SRF) on OCT; 4. Accept monthly follow-up for at least 9 months.
Exclusion criteria
Exclusion criteria: 1. Patients with other ocular diseases, especially fundus diseases; 2. Myopia above -6D; 3. Had intraocular surgery in the past 3 months, using or have used corticosteroids in the past 6 months, have received anti-VEGF therapy in the past 6 months, have received traditional laser treatment in the past 1 year, or planning to use corticosteroids within six months after receiving treatment; 4. Those who cannot accept monthly follow-up; 5. Patients with FA and ICGA contraindications, such as pregnancy, liver and kidney dysfunction, allergy to contrast agents, etc.; 6. Serum potassium >= 5.5mmol/L; 7. Taking angiotensinase inhibitors; 8. Female patients who plan to become pregnant within 9 months after treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percentage of Complete Resolution of SRF; | — |
Secondary
| Measure | Time frame |
|---|---|
| Change of BCVA;Change of CMT;Change of SFCT;Change of SRF Height;Second treatment; | — |
Countries
China
Contacts
Public ContactMeixia Zhang
West China Hospital of Sichuan University
Outcome results
None listed