diffuse axonal injury
Conditions
Interventions
Gold Standard:(1) A history of head rotation violence
(2) Clinical outcomes
(3) CT or MRI examination
(4) pathological signs of diffuse axonal injury at autopsy.
Sponsors
Hai'ning People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) With a clear history of TBI and a coma immediately after the injury; (2) CT or MRI examination shows multiple non-occupying hemorrhages (diameter 6 hours; (3) Aged 18 to 80 years old, male or female; (4) Patients and his family members informed consent and volunteered to participate in this study.
Exclusion criteria
Exclusion criteria: (1) A history of TBI, a history of cerebrovascular accident, a history of intracranial space-occupying lesions, a history of seizures, or a history of other intracranial lesions; (2) A history of mental illness or drug abuse, long-term history of alcoholism; (3) Combined Severe multiple injuries, severe liver and kidney damage, hemorrhagic shock; (4) Past history of diabetes, malignant tumors and other systemic diseases; (5) Mental restlessness or other reasons unable to cooperate with the assessment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| GOSE; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cognitive evaluation; | — |
Countries
China
Contacts
Public ContactWeiliang Chen
Hai'ning People's Hospital
Outcome results
None listed