Reference range of neonatal organ injury
Conditions
Interventions
Healthy newborn group:Nil
Sponsors
Guangzhou Women and Children's Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Term newborns (aged 0-28 days, less than 28 days).
Exclusion criteria
Exclusion criteria: 1. Gestational age: =42 weeks; 2. Birth weight: >=4000 g or < 2500g; 3. Maternal health during pregnancy (see the remarks for the specific exclusion of diseases, excluding the use of therapeutic drugs during pregnancy); 4. Perinatal knowledge of hypoxia; 5. Patients with various acute diseases within two weeks; 6. Patients with congenital diseases (inherited metabolic diseases, congenital heart diseases, etc.) diagnosed by the hospital; 7. Patients with medication history within one week: including therapeutic drugs (such as antibiotics, hormones, etc.); 8. Those who cannot sign the informed consent: those whose parents or legal guardians do not sign the informed consent. Remarks: chronic system diseases mainly include the following system diseases: amniotic fluid turbidity during pregnancy, Apgar score lower than 8 at birth, asphyxia during production, digestive system diseases (liver cirrhosis, hepatitis, fatty liver disease, cholelithiasis, cholecystitis, chronic diarrhea, inflammatory bowel disease, peptic ulcer, etc.), respiratory system diseases (pneumonia, lung malformation, etc.), circulatory system diseases Diseases of the urinary system (Henoch Schonlein purpura nephritis, nephrotic syndrome, etc.), endocrine and genetic metabolic diseases (diabetes, metabolic syndrome, dyslipidemia and dyslipidemia, hyperuricemia, ventilation, thyroid diseases, etc.), rheumatic immune diseases (rheumatoid arthritis, systemic lupus erythematosus, etc.), and allergic diseases (rheumatoid arthritis, etc.) Rash, urticaria, bronchial asthma, allergic dermatitis, atopic dermatitis, allergic rhinitis, allergic diseases of digestive system, food allergy, etc.), hematological diseases (anemia, leukemia, platelet abnormalities, etc.), malignant tumor and tumor radiotherapy and chemotherapy, burns and muscle trauma, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total albumin;Alkaline phosphatase;prealbumin;Total bilirubin;S100 beta protein;HA1c;Hypersensitive troponin;Brain natriuretic peptide;insulin;Glycosylated serum protein;Lactic acid;Total bile acid;Gama-GT;Direct bilirubin;Uric acid;Urea nitrogen;N-terminal natriuretic peptide;cystatin C;Alanine aminotransferase;Aspartic acid aminotransferase;creatinine;blood sugar; | — |
Countries
China
Contacts
Public ContactYanwei Hu
Guangzhou Women and Children's Medical Center
Outcome results
None listed