Depression
Conditions
Interventions
Depression cases:electroconvulsive therapy
Sponsors
Renmin Hospital of Wuhan University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Patient aged 18 to 60 years; 2. Patient met the following DSM-5 criteria for diagnosis of unipolar or bipolar depression; 3. Patient was competent to provide informed consent; 4. Patient was sufficiently fluent in Chinese to ensure valid responses to the neuropsychological tests.
Exclusion criteria
Exclusion criteria: 1. Failure to respond to earlier ECT; 2. ECT within the last 3 months; 3. Rapid-cycling, mixed-episode or manic bipolar disorder; 4. Inability to follow the study protocol; 5. Unstable, serious comorbid medical condition (Parkinsons disease, multiple sclerosis, stroke, alcohol use disorder, etc.) or history of epilepsy; 6. Pregnancy or women without adequate contraception.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montgomery-Asberg Depression Rating Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hamilton anxiety rating scale;Patient Health Questionnaire (PHQ-9);Generalised Anxiety Disorder Assessment (GAD-7);Clinical Global Impression;mini-mental state examination;repeatable battery for the assessment of neuropsyehological status, RBANS;Young manic rating scale; | — |
Countries
China
Contacts
Public ContactZhong-Chun Liu
Wuhan University People's Hospital
Outcome results
None listed