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To evaluate a multicenter, randomized, controlled trial of automated hydration therapy devices for the prevention of contrast agent induced acute kidney injury in high-risk patients

To evaluate a multicenter, randomized, controlled trial of automated hydration therapy devices for the prevention of contrast agent induced acute kidney injury in high-risk patients

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100044306
Enrollment
Unknown
Registered
2021-03-16
Start date
2021-04-01
Completion date
Unknown
Last updated
2021-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prevention of contrast agent - induced acute kidney injury

Interventions

Experimental group:Use an automatic hydration therapy device
control group :Routine hydration therapy

Sponsors

The General Hospital of the People's Liberation Army
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: (1) Aged >=18 years; (2) Patients with unstable angina or acute non-ST elevation myocardial infarction (refer to 2019ESC guidelines). (3) Chronic kidney disease (EGFR = 6; (4) Coronary interventional surgery has been performed.

Exclusion criteria

Exclusion criteria: (1) Pregnancy; (2) Acute pulmonary edema within 1 month; (3) Recent use of iodine contrast agent (within 72 hours); (4) To be included in other clinical trials; (5) The use of theophylline, dopamine, mannitol and/or phenoldopam; (6) Patients with end-stage renal disease and routine dialysis; (7) Cardiac shock; (8) Acute left heart failure or acute exacerbation of chronic heart failure within two weeks; (9) Clear allergy to contrast agents or diuretics; (10) There is contraindication of indwelling catheter; (11) The investigator decides that he is not suitable to participate in this study for any other reason.

Design outcomes

Primary

MeasureTime frame
CI-AKI%;

Secondary

MeasureTime frame
CI-AKI;

Countries

China

Contacts

Public ContactYunDai Chen

The General Hospital of the People's Liberation Army

cyundai@vip.163.com+86 13311119778

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026