overweight/obesity
Conditions
Interventions
Intervention group versus Control group:Dietary intervention, Exercise guidance, Medication, Regulation of intestinal microecology, Metabolic surgery versus Routine education
Sponsors
Tianjin Union Medical Center
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged between 18 and 70 years old (including 18 and 70 years); 2. Body mass index (BMI) >= 24kg/m2; 3. Subjects voluntarily sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients diagnosed with tumor within the last 5 years; 2. Unstable angina, or cardiac function is grade II or above according to New York heart associations cardiac function rating; 3. End-stage renal disease or liver disease; 4. Autoimmune diseases (such as systemic lupus erythematosus, etc.); 5. Unstable neurological and psychiatric disorders including depression/anxiety disorders, severe eating disorders such as bulimia and anorexia; 6. Those who can not take care of themselves; 7. Pregnant or lactating women; 8. Any other circumstances considered by the Investigator to be inappropriate for the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Body composition analysis;fitness test;fasting insulin;HOMA2 -IR;fasting blood glucose;blood glucose at 2 hours after taking 75g glucose; glycosylated hemoglobin;liver lipid contents measured by MRI; instantaneous elastic numerical determination of the hardness of liver;serum triglyceride level; total cholesterol level;low-density lipoprotein cholesterol level;high-density lipoprotein cholesterol level;systolic pressure;diastolic pressure;serum testosterone;estrogen;follicle stimulating hormone;luteinizing hormone;prolactin; | — |
Countries
China
Contacts
Public ContactChunjun Li
Tianjin Union Medical Center
Outcome results
None listed