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The 50% effective bolus dose of dexmedetomidine combined with S(+)-ketamine 1.0 mg/kg for drug-induced sleep endoscopy in pediatric obstructive sleep apnea

The 50% effective bolus dose of dexmedetomidine combined with S(+)-ketamine 1.0 mg/kg for drug-induced sleep endoscopy in pediatric obstructive sleep apnea

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100044299
Enrollment
Unknown
Registered
2021-03-16
Start date
2021-03-23
Completion date
Unknown
Last updated
2021-12-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obstructive sleep apnea

Interventions

Case series:The bolus dose of dexmedetomidine with S(+)-ketamine 1.0 mg/kg was induced for drug-induced sleep endoscopy in pediatric obstructive sleep apnea

Sponsors

Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Years to 12 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 2 to 12 years; 2. American Society of Anesthesiologists (ASA) physical status of I-II; 3. Physical examination findings were inconsistent with adenotonsillar hypertrophy.

Exclusion criteria

Exclusion criteria: 1. Recent upper respiratory tract infection; 2. Any contraindication for any study drug or scheduled anesthetic drug; 3. Lack of parental/guardian consent to participate.

Design outcomes

Primary

MeasureTime frame
The 50% effective bolus dose;—

Secondary

MeasureTime frame
Blood pressure;Heart rate;Oxygen saturation;—

Countries

China

Contacts

Public ContactZhang RuiDong

Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine

doctorruidong@163.com+86 18916637626

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026