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Sonazoid Contrast-Enhanced Ultrasound Imaging in the Diagnosis of Focal Liver Diseases in Different Liver Backgrounds

Sonazoid Contrast-Enhanced Ultrasound Imaging in the Diagnosis of Focal Liver Diseases in Different Liver Backgrounds

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100044289
Enrollment
Unknown
Registered
2021-03-14
Start date
2021-03-15
Completion date
Unknown
Last updated
2021-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Focal liver lesions

Interventions

Group 1:Hepatitis B and C background
Group 2:Fatty liver background
Group 3:Cirrhosis background
Group 4:Normal liver

Sponsors

Zhongshan Hospital, Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Chinese citizens aged 18 to 85 years old; 2. Routine ultrasound indicates that the liver has a clear focus, with liver parenchyma around it, and pathological tissue results can be obtained from the focus and liver parenchyma; 3. Contrast-enhanced ultrasound (showing Zhuoan) examination is possible, and there is an enhanced MRI examination result. If the enhanced MRI examination is not possible, the enhanced CT examination result should be available; for patients with liver fibrosis after hepatitis, the liver parenchymal elastography examination result can be added; 4. If the subject is a female, it should be a non-pregnant or lactating female; 5. The patient joined the study voluntarily and signed an informed consent form.

Exclusion criteria

Exclusion criteria: 1. Pregnant; 2. Routine ultrasound showed that there is no clear liver space, or there is liver space but no pathological tissue results can be obtained; 3. Unable to obtain the results of enhanced nuclear magnetic or enhanced CT; 4. The subject is known to be allergic to perfluorobutane gas or any component of Sonazoid; 5. The researcher believes that the subject is not suitable for participating in this research.

Design outcomes

Primary

MeasureTime frame
Sonazoid CEUS Performance;

Countries

China

Contacts

Public ContactDong Yi

Zhongshan Hospital, Fudan University

dong.yi@zs-hospital.sh.cn+86 13916743509

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026