postoperative cognitive dysfunction
Conditions
Interventions
Sponsors
Guangxi Medical University Cancer Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 80 years old, without severe hearing or visual impairment, and able to read; 2. ASA grade I-II; 3. No history of heart, blood and brain related system diseases; 4. Plan to perform laparoscopic surgery under general anesthesia (except liver surgery), the operation time >= 2 hours; 5. The patient and the client agree to participate in this study.
Exclusion criteria
Exclusion criteria: 1. Patients with previous depression, severe dementia, schizophrenia, epilepsy, Parkinson's history, or myasthenia gravis, who cannot cooperate in the evaluation; 2. Heart function >= Grade 3, severe renal impairment (need kidney replacement Treatment), severe liver damage (Child-Pugh grade C); 3. Have a history of craniocerebral surgery; 4. Preoperative MMSE<23 points; 5. Intraoperative hemodynamics is unstable, and the mean arterial pressure exceeds the baseline fluctuation range +/- 25% for 3 minutes; 6. Secondary hyperlipidemia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitive function; | — |
Countries
China
Contacts
Public ContactLin Fei
Guangxi Medical University Cancer Hospital
Outcome results
None listed