Major depressive disorder
Conditions
Interventions
1:LFMS
Sponsors
Beijing An Ding Hospital, Capital medical university
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1) Outpatients or inpatients, aged from 18 to 60 years old (including 18 and 60 years old), male or female; 2) According to the diagnostic criteria of major depressive disorder (Mini 5.0.0) of DSM-IV, the first episode or relapse is acceptable, without psychotic symptoms; 3) The total score of 17 item Hamilton Rating Scale for depression (HAMD-17) was more than or equal to 14; 4) The cumulative use of antidepressants in the past 14 days did not exceed 7 days; 5) Right handed; 6) Informed consent was signed by the patient.
Exclusion criteria
Exclusion criteria: 1) The patients with schizophrenia, bipolar disorder, schizophrenic affective disorder or other mental disorders were diagnosed before; 2) Alcohol and drug dependence or acute poisoning within one year; 3) Pregnant or lactating women; 4) The researchers believe that the patient has a serious risk of suicide; 5) At present, some researchers with serious physical diseases think that they are not suitable for this study; 6) In recent 6 months, the patients were treated with antipsychotic long-term injection; 7) Patients with thyroid dysfunction and need treatment before enrollment; 8) Previous history of head injury or nervous system injury or recurrent headache attack; 9) One year before entering the group, they had received electrospasmodic treatment; 10) Implanting metal objects that cannot be removed, such as dentures, artery clips, pacemakers or metal fixators; 11) Refractory depression (previously treated with two or more antidepressants for 6 weeks was ineffective); 12) There are contraindications to MRI scanning.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| brain function; | — |
Countries
China
Contacts
Public ContactLe Xiao
Beijing An Ding Hospital, Capital medical university
Outcome results
None listed