FindTrial
Sign In

Comparison of the effects of perineural or intravenous dexamethasone on Thoracic Paravertebral Block in Ivor-Lewis Esophagectomy

Comparison of the effects of perineural or intravenous dexamethasone on Thoracic Paravertebral Block in Ivor-Lewis Esophagectomy

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100044278
Enrollment
Unknown
Registered
2021-03-14
Start date
2021-04-06
Completion date
Unknown
Last updated
2022-01-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophagectomy

Interventions

I.v. dexamethasone (Dex-IV):Dexamethasone 0.15mg/kg iv
Perineural dexamethasone (Dex-PN):Dexamethasone 0.15mg/kg perineural

Sponsors

Xuzhou Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Aged between 40 to 70 years; 2. ASA I-III; 3. Patients undergo Ivor-Lewis Esophagectomy; 4. BMI 18.5 kg/m^2 to 30 kg/m^2.

Exclusion criteria

Exclusion criteria: 1. Patients refused to write informed consent; 2. Coagulation dysfunction or treatment with anticoagulant drugs; 3. Allergic to local anesthetics; 4. Severe the spine or chest deformity; 5. Local infection; 6. History of patients taking analgesic drugs; 7. Patients who could not complete the VAS pain score.

Design outcomes

Primary

MeasureTime frame
Duration of analgesia;VAS score at rest;VAS score at coughing;—

Secondary

MeasureTime frame
Plasma cortisol concentration;Plasma cortisol concentration;Remedial analgesic use;—

Countries

China

Contacts

Public ContactLiwei Wang

Xuzhou Central Hospital

doctorlww@sina.com+86 18952170255

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026