Relationship between early goal-directed therapy and prognosis of patients undergoing liver transplantation

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100044257

Enrollment

Unknown

Registered

2021-03-12

Start date

2021-04-01

Completion date

Unknown

Last updated

2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

liver transplantation

Interventions

Experimental group:early goal-directed therapy

control group:conventional therapy

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. All patients after liver transplantation,age of 18 or older; 2. Meet at least of one following: the lactic of 4mmol/L or more; circulatory shock(systolic blood pressure<90mmHg or 40mmHg less than base level; SOFA score is increaded by two points or more than preoperative); 3. Obtain informed consent.

Exclusion criteria

Exclusion criteria: Patients expected to be out of ICU in next 48 hours.

Design outcomes

Primary

Measure	Time frame
guanylate-binding protein 2;myoglobin;calprotectin;T cell;B cell;NK cell;Treg cell;cell-free DNA;DNA methylation;????????;	—

Countries

China

Contacts

Public ContactHuang Lifeng

Beijing Chaoyang Hospital of Capital Medical University

burnshlf@sina.cn+86 13621225990

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 14, 2026