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Application of High Flow Nasal Cannular on Preoxygenation During Induction of Frame-Based Stereoelectroencephalography Surgery: a Prospective Randomized Controlled Clinical Study

Application of High Flow Nasal Cannular on Preoxygenation During Induction of Frame-Based Stereoelectroencephalography Surgery: a Prospective Randomized Controlled Clinical Study

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100044239
Enrollment
Unknown
Registered
2021-03-12
Start date
2021-05-20
Completion date
Unknown
Last updated
2021-09-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia of frame-based stereoelectroencephalography surgery

Interventions

Mask Group:oxygen inhalation and ventilation using mask during peri-intubation period
HFNC Group:pre-oxygenation high-flow nasal oxygen inhalation during peri-intubation period

Sponsors

The First Affiliated Hospital of University of Science and Technology of China
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Frame-based stereoelectroencephalography surgery patients under gerenal anesthesia; 2. Aged 18 to 65 years; 3. ASA I~III level.

Exclusion criteria

Exclusion criteria: 1. Severe psychiatric disorders; 2. Significant raised intracranial pressure; 3. Mallampati grade III or IV; 4. Anatomical factors precluding use of a face mask or nasal cannula,upper airway obstruction; 5. Body mass index > 35kg/m2; 6. Severe hypoxemia, SPO2<90% in ambient air; 7. Moderate or severe anemia, preoperative hemoglobin<90g/L; 8. Severe cardiovascular or cerebrovascular disease; 9. Severe hepatic and renal dysfunction, electrolyte and acid-base disorder; 10.Severe respiratory disease.

Design outcomes

Primary

MeasureTime frame
the lowest of SPO2;PaO2 after tracheal intubation;

Secondary

MeasureTime frame
Vital signs at defined time points;ABG analysis at defined time points;-time successful intubation rate;Time taken for successful intubation;Duration of face mask or HFNC application;Satisfaction of Anesthesiologists;Patients' tolerance;Using of airway adjunct;Early complications: airway dry/discomfort, gastric insufflation, nausea and vomiting, elicited as patients leave PACU.;D-value of PaCO2 and PaO2 before and after intubation;

Countries

China

Contacts

Public ContactLi Juan

The First Affiliated Hospital of University of Science and Technology of China

huamuzi1999@163.com+86 13956005465

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026