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A multicenter cohort study on maternal and infant microecology and new targets for pre-eclampsia screening in China

A multicenter cohort study on maternal and infant microecology and new targets for pre-eclampsia screening in China

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100044232
Enrollment
Unknown
Registered
2021-03-12
Start date
2021-04-01
Completion date
Unknown
Last updated
2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pre-eclampsia

Interventions

Case series:No

Sponsors

Zhujiang Hospital of Southern Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Aged >=18 years; 2. pregnancy woman; 3. with a singleton pregnancy; 4. volunteer and receive regular antenatal examinations in the research centers; 5. volunteer to sign a written informed consent.

Exclusion criteria

Exclusion criteria: 1. Concurrent with hypertension, diabetes, liver and kidney diseases, hematonosis and other serious diseases of pre-pregnancy women, including patients requiring long-term medication for primary diseases; 2. With history of preeclampsia; 3. Tumor patients concurrent with serious infection requiring long-term drug treatment; 4. Pregnant women conceiving through in vitro fertilization; 5. Multiple pregnancies; 6. Patients with clear indications of medical pregnancy termination during early pregnancy; 7. Any medical or non-medical conditions deemed inappropriate for study participation according to the investigator.

Design outcomes

Primary

MeasureTime frame
peptidomics;microbiome;resistance index;pulsatility index;placental growth factor;

Countries

China

Contacts

Public ContactHongwei Zhou

Zhujiang Hospital of Southern Medical University

biodegradation@gmail.com+86 020-62783355

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026