opioid
Conditions
Interventions
OFA group: Dexmedetomidine-Esketamine-Lidocaine
OA group:propofol-sufentanil-remifentanil
Sponsors
Department of Anesthesiology, Nanjing Maternal and Child Health Hospital
Eligibility
Sex/Gender
Female
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Aged 20 to 60 years; 2. ASA III; 3. No previous history of surgical anesthesia; 4. All patients had no preoperative infection and fever; 5. No preoperative chemotherapy or radiotherapy; 6. No autoimmune diseases; 7. No endocrine and metabolic diseases; 8. Normal liver and kidney function.
Exclusion criteria
Exclusion criteria: 1. Patients with preoperative serious heart or lung disease or mental problems (chronic depression or severe bipolar disorder); 2. Patients who continue to take steroid hormones; 3. Long-term use of opioid or opioid abuse; 4. Allergic to any drug in the test; 5. Patients with a history of hypertension.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| pain;The cases of receiving dezocine; | — |
Secondary
| Measure | Time frame |
|---|---|
| mean arterial pressure;heart rate;adverse reaction; | — |
Countries
China
Contacts
Public ContactShanwu Feng
Department of Anesthesiology, Nanjing Maternal and Child Health Hospital
Outcome results
None listed