Idiopathic epimacular membrane
Conditions
Interventions
experimental group:intravitreal injection of ozurdex
control group:Nil
Sponsors
Tianjin Medical University Eye Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged >= 40 years; 2. The diagnosis of idiopathic epimacular membrane requires vitrectomy combined with membrane peeling; 3. There was no injection of anti angiogenic factor drugs within 3 months before or after operation; 4. At least part of the cornea is transparent (or the central area of the cornea is transparent), which can ensure the fundus examination, visual function examination and OCT examination after vitrectomy.
Exclusion criteria
Exclusion criteria: 1. Have participated in other clinical trials within 4 weeks before the start of this study, or have received intrabulbar injection of this drug or other drugs within 3 months before the start of this study; 2. Known adverse reactions to ozurdex or triamcinolone acetonide (TA); 3. Glaucoma with high intraocular pressure or definite diagnosis (including steroid glaucoma); 4. Previously had proliferative diabetic retinopathy, retinal vascular disease, and proliferative vitreoretinopathy; 5. Suspected or confirmed infectious lesions around the eyes (herpes simplex virus, varicella zoster virus, bacterial infection, fungal infection, etc.); 6. Patients with previous congenital eye abnormalities, ocular trauma, and eye diseases seriously affecting vision; 7. Pregnant or lactating women; 8. Patients with mental history.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| vision;central macular thickness; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraocular pressure;Multifocal electrophysiology;microperimetry;octa; | — |
Countries
China
Contacts
Public ContactShao Yan
Tianjin Medical University Eye Hospital
Outcome results
None listed