New techniques and methods for accurate diagnosis of pathogens in pediatric patients with severe infection

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100044224

Enrollment

Unknown

Registered

2021-03-12

Start date

2021-05-01

Completion date

Unknown

Last updated

2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

severe infection

Interventions

Gold Standard:Clinical outcome

Index test:NGS

Eligibility

Sex/Gender

All

Age

No minimum to 18 Years

Inclusion criteria

Inclusion criteria: 1. Aged 28 days to 18 years old; 2. hospitalized patients suspected severe infection in pediatric intensive care unit.

Exclusion criteria

Exclusion criteria: 1. Non-infectious causes of fever, such as connective tissue disease and central hyperthermia; patients with contraindications for fiberoptic bronchoscopy; 2. patients who died within 24 hours of PICU or gave up treatment when the diagnosis was not yet clear.

Design outcomes

Primary

Measure	Time frame
SEN, SPE, ACC, AUC of ROC;	—

Countries

China

Contacts

Public ContactLu Guoping

Children's Hospital of Fudan University

13788904150@163.com+86 13788904150

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026