Ischemic Stroke
Conditions
Interventions
1:do not use tirofiban
2:full dose tirofiban
3:2/3 full dose tirofiban
4:1/3 full dose tirofiban
Sponsors
Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Above the age of 18 years; (2) In stroke patients with great vessel occlusion, the onset of anterior circulation occlusion was less than 6 h, and the onset of anterior circulation occlusion was less than 6-24 h after rigorous imaging screening, the onset of posterior circulation great vessel occlusion was less than 24 h; (3) CT excluded intracranial hemorrhage and subarachnoid hemorrhage; (4) Acute ischemic stroke, imaging examination confirmed as great vessel occlusion; (5) Informed consent signed by the patient or legal representative.
Exclusion criteria
Exclusion criteria: (1) If arterial thrombolysis is performed, the contraindication criteria for intravenous thrombolysis are referred. (2) active bleeding or known bleeding tendency; (3) serious heart, liver and renal insufficiency; (4) Blood glucose 22.2 mmol/L; (5) Severe hypertension that cannot be controlled by drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NIHSS??;Intracranial bleeding; | — |
Secondary
| Measure | Time frame |
|---|---|
| mRS??;thrombolysis in Cerebral Infarction classification; | — |
Countries
China
Contacts
Public ContactXu Danhua
Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine
Outcome results
None listed