Postpartum Depression
Conditions
Interventions
Esketamine Group:Esketamine
Sponsors
Mengcheng County No.1 People's Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: (1) Aged 18 --45 years; (2) ASA II; (3) More than 28 weeks of gestation; (4) Postoperative analgesia was required; (5) No serious cardiovascular and cerebrovascular diseases were found; (6) The puerpera can communicate well with the follow-up; (7) Volunteer to participate in this study and sign the relevant informed consent.
Exclusion criteria
Exclusion criteria: (1) There were pregnancy induced hypertension, thyroid dysfunction, preeclampsia and eclampsia, psychosis, inability to communicate pain response; (2) Abnormal increase of uterine activity, such as ankylosing uterine contraction, placental abruption and umbilical cord prolapse; (3) Contraindications of epidural catheterization such as history of spinal trauma or deformity; (4) Opioid allergy or history of opioid abuse; (5) Patients with severe risk of elevated blood pressure or intracranial pressure; (6) Patients with poorly controlled or untreated hypertension; (7) The fetus was seriously abnormal; (8) Pernicious placenta previa; (9) The patients who have received labor analgesia; (10) Other conditions considered by the researchers to be unsuitable for further treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postpartum depression at 1 month;Pain score of Parturient and times of analgesia pump pressing within 48 hours after delivery;Sleep quality of Parturient at 1d, 7d and 1 monthafter delivery; | — |
Secondary
| Measure | Time frame |
|---|---|
| BP, HR, SpO2, ECG and RR at the time points of intraoperative anesthesia (T0), 2 min after anesthesia (T1), fetal delivery (T2), 5 min after fetal delivery (T4) and leaving the operating room (T4).;Perioperative consumption of analgesics; | — |
Countries
China
Contacts
Public ContactXiaoqiang Zhang
Mengcheng County No.1 People's Hospital
Outcome results
None listed