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Safety and efficacy of remimazolam besylate combined with alfentanil hydrochloride in hysteroscopy

Safety and efficacy of remimazolam besylate combined with alfentanil hydrochloride in hysteroscopy

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100044177
Enrollment
Unknown
Registered
2021-03-12
Start date
2021-05-01
Completion date
Unknown
Last updated
2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abnormal uterine bleeding

Interventions

Remimazolam + alfentanil group (RA group):Remimazolam + alfentanil
Remimazolam + remifentanil group (RR group):Remimazolam + remifentanil

Sponsors

Mengcheng County No.1 People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. The subjects voluntarily participated and signed the informed consent; 2. They were 18-65 years old; 3. ASA grade is I-II; 4. Body mass index (BMI) 19-30kg / m2; 5. Patients scheduled for hysteroscopy.

Exclusion criteria

Exclusion criteria: 1. History of alcohol abuse or general anesthesia drug allergy; 2. Emergency patients or patients with acute inflammation; 3. Patients with impaired liver or kidney function; 4. Dementia or severe cognitive impairment; 5. Anyone with communication difficulties. 6. Pregnant and lactating women.

Design outcomes

Primary

MeasureTime frame
MOAA/S score;Sedative dosage;Dosage of analgesics;Incidence of adverse reactions;

Secondary

MeasureTime frame
The changes of systolic blood pressure, diastolic blood pressure, heart rate, moaA / s score and SpO2 were observed and recorded before anesthesia (T0), 2 minutes after anesthesia (T1), at the time of cervical dilatation (T2), at the end of operation (T3) and at the time of recovery (T4).;

Countries

China

Contacts

Public ContactXiaoqiang Zhang

Mengcheng County No.1 People's Hospital

zxqahl@126.com+86 13309670321

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 11, 2026