Relationship between Corneal Sensation, Blinking and Tear Film in Patients with Neurotrophic Keratitis

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100044068

Enrollment

Unknown

Registered

2021-03-09

Start date

2021-03-10

Completion date

Unknown

Last updated

2021-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neurotrophic Keratitis

Interventions

NK??:none

controls:none

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The patients who was diagnosed as neurotrophic keratitis, which was showed as loss of cornea sensation, dry eyes, epithelial breakdown and corneal ulceration. 30 healthy people with age and sex matching were included as controls.

Exclusion criteria

Exclusion criteria: Patients with corneal diseases who had normal corneal sensation.

Design outcomes

Primary

Measure	Time frame
Tears height;NITBUT;lipid layer thickness;partial blinking;Corneal sensation;nerve density;OSDI questionnaire;	—

Countries

China

Contacts

Public ContactRuihua Wei

Tianjin Medical University Eye Hospital

rwei@tmu.edu.cn+86 13920685016

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 13, 2026