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Multi-omics study on the relationship between intestinal flora and the youth of patients with ACS: Multi-center case-control study clinical trial protocol

Multi-omics study on the relationship between intestinal flora and the youth of patients with ACS: Multi-center case-control study clinical trial protocol

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100044066
Enrollment
Unknown
Registered
2021-03-09
Start date
2021-05-10
Completion date
Unknown
Last updated
2021-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with acute coronary syndrome (ACS)

Interventions

Young group (18 <=age <=44 years):Nil
Elderly group(60 <= age <= 85 years):Nil

Sponsors

Tangdu Hospital of Air Force Millitary Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: Meeting all of the following criteria can be included: 1. Clinical manifestations of chest pain (typical or atypical); 2. 18 years old = 70%; 8. Signed written informed consent.

Exclusion criteria

Exclusion criteria: Exclusion criteria (Subject meeting any of the following criteria will be excluded) : Those who have one or more of the following will not be included in the study: 1. Patients with severe autoimmune diseases or malignant tumors; 2. Patients with severe liver, kidney, brain and lung dysfunction; 3. Patients with a history of surgery, trauma or acute or chronic infection within 1 month; 4. Patients' life expectancy <= 12 months; 5. Have a history of gastrointestinal surgery in the previous year or have used antibiotics for more than 3 days in the previous 3 months; 6. The investigator judged that the patients were not suitable for participating in the study for other reasons; 7. The researcher judged that patients had poor compliance and could not complete the study as required; 8. Patients participating in other clinical trials (other than other subjects of the project) who did not meet the time limit for the primary study endpoint.

Design outcomes

Primary

MeasureTime frame
Intestinal microbial community composition and plasma metabolite levels;

Secondary

MeasureTime frame
Spearman correlation coefficient between different plasma metabolites and different flora;Chi-square value of classified variable and T value of continuous variable in risk factors;

Countries

China

Contacts

Public ContactLi Yan

Tangdu Hospital of Air Force Millitary Medical University

307712565@qq.com+86 13892890227

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026