nonalcoholic fatty liver disease
Conditions
Interventions
control group:Diet control and exercise
treatment group A:Diet control and exercise plus oral vitamin D3 400IU daily
treatment group B:Diet control and exercise plus oral vitamin D3 800IU daily
Sponsors
Wuhan Hankou Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Patients aged 18-75 years old with non-alcoholic fatty liver disease who meet the diagnostic criteria in the Guidelines for the Prevention and Treatment of Non-alcoholic Fatty Liver Disease (2018 Update) issued by the Fatty Liver and AlcoAlcoic Liver Disease Research Group of the Chinese Association of Liver Diseases.
Exclusion criteria
Exclusion criteria: (1) Alcoholic liver disease, viral hepatitis, autoimmune liver disease, Wilson's disease, drug-induced liver injury, undefined abnormal liver function, cirrhosis, and liver tumors. (2) Malignant tumor, liver abscess and biliary tract disease. (3) Patients with diabetes mellitus, anemia, severe cardiovascular and cerebrovascular diseases, renal insufficiency, parathyroid disease, or taking drugs that affect vitamin D metabolism within the last 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum vitamin D3;Related indexes of iron metabolism; | — |
Secondary
| Measure | Time frame |
|---|---|
| Liver function;Insulin resistance index;Inflammatory cytokines; | — |
Countries
China
Contacts
Public ContactLiu Zhiping
Wuhan Hankou Hospital
Outcome results
None listed