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The analgesia effect of topical application of esketamine for postoperative sore throat in patients undergoing double-lumen endobronchial intubation: a prospective, random and controlled study

The analgesia effect of topical application of esketamine for postoperative sore throat in patients undergoing double-lumen endobronchial intubation: a prospective, random and controlled study

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100044061
Enrollment
Unknown
Registered
2021-03-09
Start date
2021-10-31
Completion date
Unknown
Last updated
2023-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative sore throat

Interventions

Esketamine group:Esketamine gargle before intubation
Control group:Normal saline gargle before intubation

Sponsors

Third Affiliated Hospital of Sun Yat-Sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients with ASA grade I-III, aged 18 to 70 years and scheduled for elective thoracic surgery requiring tracheal intubation were included.

Exclusion criteria

Exclusion criteria: Patients who had a Mallampati score of IV, pre-existing sore throat or hoarseness, recent or recurrent respiratory tract infection, tracheostomy tube, predicted postoperative aspiration, known or predicted difficult airway, or contraindications to esketamine were excluded. Patients who had a Cormack-Lehane grade III or IV laryngoscopic view, required orogastric or nasogastric tubes during mask ventilation, or required postoperative mechanical ventilation were also excluded.

Design outcomes

Secondary

MeasureTime frame
The incidence of sore throat;Severity of sore throat and incidence of hoarseness;Intraoperative haemodynamic responses;Postoperative wound pain scores;

Primary

MeasureTime frame
The incidence of sore throat;

Countries

China

Contacts

Public ContactXiang Li

The Third Affiliated Hospital, Sun Yat-Sen University

lixiang27@mail.sysu.edu.cn+86 156 0239 1780

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026