Study on the application of antibiotics in children with severe infection based on active therapeutic drug monitoring

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100044049

Enrollment

Unknown

Registered

2021-03-09

Start date

2021-05-01

Completion date

Unknown

Last updated

2021-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Severe infections in children

Interventions

case series:Nil

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. According to the 2010 "Guidelines for Rescue of Sepsis" [16] Children aged 29 days to 18 years with a diagnosis of sepsis; 2. Children in the CRRT group are expected to receive CRRT treatment for at least 4 days and can complete the planned blood collection plan; 3. There are clinical indications for antibiotic use; 4. Blood can be drawn from arterial catheter or CRRT, ECMO circuit; 5. Parents or legal guardians of the child are required to sign an informed consent form.

Exclusion criteria

Exclusion criteria: The terminally ill child may be expected to be extremely ill and cannot complete the planned blood collection program.

Design outcomes

Primary

Measure	Time frame
Drug Plasma Concentration;	—

Countries

China

Contacts

Public ContactLu Guoping

Children's Hospital of Fudan University

13788904150@163.com+86 13788904150

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026