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Effect of preoperative pain sensitization on neurocognitive function of elderly patients during perioperative period and anesthesia management

Effect of preoperative pain sensitization on neurocognitive function of elderly patients during perioperative period and anesthesia management

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100044041
Enrollment
Unknown
Registered
2021-03-09
Start date
2021-03-10
Completion date
Unknown
Last updated
2021-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

perioperative neurocognitive function disorder

Interventions

group C:CSI score= 40points

Sponsors

The Third Hospital of Hebei Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 85 Years

Inclusion criteria

Inclusion criteria: BMI18.5~24.0 kg/m2, gender is not limited, ASA grade I~III, aged 60~85 years.

Exclusion criteria

Exclusion criteria: (1) History of recovery from surgery and anesthesia; (2) Alcohol abusers; (3) Smokers; (4) Patients with obvious abnormal liver and kidney function; (5) Past history of severe cardiovascular and cerebrovascular diseases; (6) History of lung disease; (7) Patients with severe vision and hearing impairment; (8) Those who cannot communicate normally; (9) Delirium, dementia, Alzheimers disease and Parkinsons disease; (10) Those who do not cooperate cannot complete the test.

Design outcomes

Primary

MeasureTime frame
Central Sensitization Inventory;Mini-Mental State Examination(MMSE);Montreal Cognitive Assessment (MoCA);digital clock drawing test;Glasgow Coma Scale (GCS);Confusion Assessment Method-Chinese Reversion (CAM-CR);Numerical Rating Scale (NRS);

Secondary

MeasureTime frame
Pittsburgh Sleep Quality Index (PSQI);Hospital Anxiety and Depression Scale (HAD);WOMAC score;basic informations and clinical characteristics of patients;Patient Recovery Quality Score;perioperative analgesics consumption and Richmond Agitation Sedation Scale;Patient satisfaction score;QST;PPTs;Thermal pain threshold, thermal pain tolerance, suprathreshold thermal pain response;Neuropsychological cognition related score;The Geriatric Depression Scale;The Pain Catastrophizing Scale;Geriatric Depression Scale (GDS);

Countries

China

Contacts

Public ContactWang Qiujun

Department of Anesthesiology, The Third Hospital of Hebei Medical University

13933178001@163.com+86 13933178001

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026