perioperative neurocognitive function disorder
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: BMI18.5~24.0 kg/m2, gender is not limited, ASA grade I~III, aged 60~85 years.
Exclusion criteria
Exclusion criteria: (1) History of recovery from surgery and anesthesia; (2) Alcohol abusers; (3) Smokers; (4) Patients with obvious abnormal liver and kidney function; (5) Past history of severe cardiovascular and cerebrovascular diseases; (6) History of lung disease; (7) Patients with severe vision and hearing impairment; (8) Those who cannot communicate normally; (9) Delirium, dementia, Alzheimers disease and Parkinsons disease; (10) Those who do not cooperate cannot complete the test.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Central Sensitization Inventory;Mini-Mental State Examination(MMSE);Montreal Cognitive Assessment (MoCA);digital clock drawing test;Glasgow Coma Scale (GCS);Confusion Assessment Method-Chinese Reversion (CAM-CR);Numerical Rating Scale (NRS); | — |
Secondary
| Measure | Time frame |
|---|---|
| Pittsburgh Sleep Quality Index (PSQI);Hospital Anxiety and Depression Scale (HAD);WOMAC score;basic informations and clinical characteristics of patients;Patient Recovery Quality Score;perioperative analgesics consumption and Richmond Agitation Sedation Scale;Patient satisfaction score;QST;PPTs;Thermal pain threshold, thermal pain tolerance, suprathreshold thermal pain response;Neuropsychological cognition related score;The Geriatric Depression Scale;The Pain Catastrophizing Scale;Geriatric Depression Scale (GDS); | — |
Countries
China
Contacts
Department of Anesthesiology, The Third Hospital of Hebei Medical University