type 2 diabetes and obesity
Conditions
Interventions
Type 2 diabetes group:Nil
Non-diabetic group:Nil
Sponsors
Department of Thyroid Biliary Deweighting and Metabolic Surgery, the Fourth Clinical College Affiliated to China Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Tissue samples were obtained from the metabolic disease biospecimen bank of the Fourth Hospital of China Medical University, and the ethical approval was done by the Ethics Committee of the Fourth Hospital of China Medical University, approval number:EC-2020-KS-004, and the sample providers were informed and signed the informed consent form. Patients undergoing laparoscopic sleeve gastrectomy (LSG), laparoscopic gastric bypass (LRYGB), and laparoscopic gastric sleeve resection + jejunostomy (LSG+JJB) were selected (20 diabetic patients and 20 non-diabetic patients of both sexes in proportion to the sample pool), liver tissue, large omental adipose tissue, subcutaneous adipose tissue, and blood samples were collected.
Exclusion criteria
Exclusion criteria: (i) chronic or acute inflammatory disease (based on medical history, blood leukocyte count and/or CRP); (ii) viral hepatitis; (iii) human immunodeficiency virus (HIV) infection, acquired immunodeficiency syndrome and immune system disorders; (iv) antibiotic therapy or oral probiotics within 3 months; (v) history of gastrointestinal surgery; (vi) gastrointestinal bleeding, inflammatory bowel disease; and (vii) malignancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 16S rRNA; | — |
Countries
China
Contacts
Public ContactYong Wang
The Fourth Affiliated Hospital of China Medical University
Outcome results
None listed