glucose and lipid metabolism disorder
Conditions
Interventions
Placebo group:placebo
Resveratrol 100mg/d group:Resveratrol 100mg/d
Resveratrol 300mg/d group:Resveratrol 300mg/d
Resveratrol 600mg/d group:esveratrol 600mg/d
Resveratrol 800mg/d group:Resveratrol 800mg/d
Sponsors
Department of Nutrition, School of Public Health, Sun Yat-Sen University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Ordinarily resident in Guangzhou, 35-70 years of age. 2. Subjects were diagnosed of dyslipidemia if they satisfified 1 or more of the following 4 conditions : - serum fasting total cholesterol (TC) level >= 5.20 mmol/L (200 mg/dL). - fasting triglyceride (TG) level >= 1.70 mmol/L (150 mg/dL). - fasting low-density lipoprotein cholesterol (LDL-C) level >= 3.12 mmol/L (120 mg/dL). - fasting HDL-C level <= 0.91 mmol/L (35 mg/dL). 3. Subjects with dyslipidemia who also had prediabetes (defined as a fasting glucose level of 5.6–6.9 mmol/L, impaired glucose tolerance with glucose level of 7.8–11.0 mmol/L, or glycated hemoglobin (HbA1c) of 5.7–6.4% ) were also recruited. 4. Willing to maintain habitual diet, physical activity pattern, and body weight throughout the trial.
Exclusion criteria
Exclusion criteria: 1. Intake of any medicine in the last 6 months that could affect lipid and glucose metabolism. 2. Intake of any dietary supplementation with phytochemicals including resveratrol in the preceding 2 months. 3. history of acute or chronic infectious disease, autoimmune disease, cancer, traumatic injury, or surgery in the preceding 1 month. 4. history of severe chronic disease including atherosclerosis and CVD, liver or renal dysfunction. 5. lactation or pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| serum lipid; | — |
Countries
China
Contacts
Public ContactLing Wenhua
Department of Nutrition, School of Public Health, Sun Yat-Sen University
Outcome results
None listed