colorectal cancer
Conditions
Interventions
Combined group:1.Traditional Chinese Medicine therapy: Tusizi (Cuscuta chinensis Lam.) , Tengligen (Actinidia arguta ), Sangjisheng (Taxillus chiensis (DC.) Danser) , Qianshi(Euryale ferox), Baihuashe
Capecitabine at a dose of 1000 mg/m2, taken orally twice a day from day 1 to day 14. The interval between each chemotherapy cycle is 21 days, with a cycle lasting 35 days, and the treatment continues
Control group:Chemotherapy with the XELOX regimen alone is carried out. The interval between each chemotherapy cycle is 7 days, with one cycle lasting 21 days. The treatment continues for 6 cycles. Re
Sponsors
Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Patients with stage IV colorectal cancer confirmed according to the diagnostic criteria outlined in the Chinese Colorectal Cancer Diagnosis and Treatment Guidelines (2017 Edition); 2. No radical surgery, radiotherapy, chemotherapy, or other treatments were received after the diagnosis of stage IV disease; 3. Karnofsky Performance Score (KPS) > 60 points; 4. Age >18 years with no gender restrictions; 5. Expected survival time >= 3 months; 6. Patients provided informed consent and are willing to undergo follow-up; 7. Complete baseline patient information is available.
Exclusion criteria
Exclusion criteria: 1. Patients with BRAF, RAS, or VEGF gene mutations; 2. Patients with a history of mental illness; 3. Patients with hepatic or renal insufficiency; 4. Patients with concurrent cancer; Those who meet any of the above criteria will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Progression-Free Survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| Disease Control Rate;Karnofsky Performance Status;Traditional Chinese Medicine syndrome score; | — |
Countries
China
Contacts
Public ContactFenggang Hou
Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine
Outcome results
None listed