A clinical study on the optimal tourniquet pressure for elderly obese patients undergoing total knee arthroplasty

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100043985

Enrollment

Unknown

Registered

2021-03-06

Start date

2021-04-01

Completion date

Unknown

Last updated

2021-07-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis

Interventions

Group A:The tourniquet pressure is set to traditional value

Group B:The tourniquet pressure is set to LOPmmHg

Group C:The tourniquet pressure is set to (LOP-10) mmHg

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged >= 65 years, BMI >= 30kg/m2, unilateral TKA is planned; 2. ASA classification I-II level; 3. Receive surgical treatment for the first time after diagnosis; 4. Consent to the use of inflatable tourniquets during the operation or without contraindications to the use of tourniquets; 5. Complete clinical data.

Exclusion criteria

Exclusion criteria: 1. Peripheral limp; 2. Severe anemia; 3. Any contraindications of regional anesthesia; 4. Severe cardiopulmonary insufficiency; 5. Abnormal blood coagulation function.

Design outcomes

Primary

Measure	Time frame
Intraoperative blood loss;Malondialdehyde;Surgeon's evaluation of tourniquet performance;	—

Countries

China

Contacts

Public ContactDong Buhuai

Xi'an Red Cross Hospital

dongbuhuai@126.com+86 13991898846

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026