acute radiation-induced esophagitis
Conditions
Interventions
control group:placebo
Sponsors
Shanxi Provincial Hospital of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Those with a confirmed diagnosis of esophageal squamous cell carcinoma by gastroscopy and pathological cytohistology (AJCC 8th edition). 2. Age greater than 18 years. 3. Patients without indications for surgery or refusing surgery. 4. No previous radiation therapy. 5. No contraindication to radiation therapy. 6. ECOG (Eastern Cooperative Oncology Group) score 0-2. 7. Those with expected survival time > 12 weeks. 8. Those who signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Complete esophageal obstruction, deep esophageal ulcer, esophageal perforation or vomiting of blood. 2. History of surgery within 28 days prior to baseline. 3. Participation in other interventional clinical trials within 30 days. 4. Pregnant and lactating women. 5. Those with severe cardiac, pulmonary, hepatic, or renal abnormalities, or immunodeficiency. 6. Those with uncontrollable psychiatric disorders, tumor metastatic disease (according to the AJCC 8th edition M1b). 7. Any other condition that the investigator deems the patient unsuitable for the clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of acute radiation esophagitis;Clinical classification of acute radiation esophagitis; | — |
Secondary
| Measure | Time frame |
|---|---|
| The occurrence time and duration of acute radiation esophagitis;Pain index;Dysphagia;Quality of Life Score (QOL-C30); | — |
Countries
China
Contacts
Public ContactXixing Wang
Shanxi Institute of Traditional Chinese Medicine
Outcome results
None listed