high-risk HPV persistent infection
Conditions
Sponsors
Anhui Province Maternity and Child Healthcare Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Women between 18 and 70 years old with sexual life, but non-pregnant or lactating; (2) Persistent hrHPV infection for more than twelve months; (3) For each individual patient, only either HPV genotyping test or HPV E6/E7 mRNA assay was used for the examination of hrHPV infection during whole observation from the screening of enrollment to the end of follow-up; (4) Without a high level of cervical lesions [no more than grade one cervical intraepithelial neoplasia (CIN I) according to the examination of colposcopy and biopsy]; (5) No previous anti-HPV intervention.
Exclusion criteria
Exclusion criteria: (1) With a history of allergy, smoking, oral contraceptive and HPV vaccination; (2) With severe heart, lung, liver and kidney dysfunction; (3) Women who cant complete the designed drug administration due to menstrual disorder.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HPV E6E7 mRNA;HPV-DNA genotyping test; | — |
Countries
China
Contacts
Public ContactShuguang Zhou
Anhui Province Maternity and Child Healthcare Hospital
Outcome results
None listed