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Establishment and validation of evaluation model for efficacy of DEB-TACE in hepatocellular carcinoma based on miRNAs AI technology

Establishment and validation of evaluation model for efficacy of DEB-TACE in hepatocellular carcinoma based on miRNAs AI technology

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100043969
Enrollment
Unknown
Registered
2021-03-06
Start date
2021-04-01
Completion date
Unknown
Last updated
2021-07-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

liver cancer

Interventions

DEB-TACE:Nil

Sponsors

Sichuan Cancer Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. The patients were 18-80 years old, and the estimated survival time was more than 3 months; 2. Gender is not limited; 3. HCC patients were diagnosed according to the criteria for diagnosis and treatment of primary liver cancer (version 2019) or pathological biopsy; 4. HCC lesions were in BCLC-B/C stage; 5. The child Pugh score of liver function was less than or equal to 7; 6. ECOG score <= 1; 7. The patients who did not receive chemoradiotherapy, ablation, immunotherapy and molecular targeted therapy before DEB-TACE for the first time; 8. Patients and / or family members agreed to participate in the clinical trial and signed an informed consent form.

Exclusion criteria

Exclusion criteria: 1. The main portal vein was completely embolized with less collateral vessels; 2. The coagulation function decreased seriously and could not be corrected; 3. The heart, lung, kidney, brain and other organs were seriously incompetent; 4. The tumor volume was more than 70% of the liver volume; 5. Patients with history of other tumors; 6. HCC recurred after surgery.

Design outcomes

Primary

MeasureTime frame
Tumor efficacy;miRNA;

Countries

China

Contacts

Public ContactXuegang Yang

Sichuan Cancer Hospital

yanggangxue@163.com+86 13683476844

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026