Skip to content

To explore the neural network regulatory mechanism mediated by acupuncture in diarrhea-predominant irritable bowel syndrome based on resting-state functional MRI

To explore the neural network regulatory mechanism mediated by acupuncture in diarrhea-predominant irritable bowel syndrome based on resting-state functional MRI

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100043967
Enrollment
Unknown
Registered
2021-03-06
Start date
2021-04-01
Completion date
Unknown
Last updated
2021-07-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

diarrhea-predominant irritable bowel syndrome

Interventions

experimental group:acupuncture
control group:sham acupuncture

Sponsors

The Affiliated Hospital of Nanjing University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 55 Years

Inclusion criteria

Inclusion criteria: 1.Meeting the IBS-D Rome IV diagnostic criteria. 2.Age range between 18-55 years old, disease course more than 6 months, right-handed; 3.Baseline IBS-SSS was more than 75; 4.Neither receiveing medication for at least 2 weeks nor receiveing other acupuncture treatments in the past 3 months before taking part in this projject; 5.Volunteer to participate in this research project and sign informed consent; 6.No metal substances in vivo.

Exclusion criteria

Exclusion criteria: 1.Other subtypes that meeting Rome IV diagnostic criteria; 2.Those who with organic intestinal diseases, hyperthyroidism, diabetes and other systemic diseases that affect the motility of the gastrointestinal tract; gastrointestinal surgery history; 3.Taking drugs,acupuncture or other treatments that may affect gastrointestinal function and intervention effectiveness; 4.With cardia-cerebrovascular disease , systemic diseases such as liver, lung, kidney, and mental and psychological diseases, or with mental and psychological diseases; 5.During pregnancy, lactation or within 1 year of childbirth; 6.People with severe fear of needles, metal allergy or allergies; claustrophobia, living implants (such as cochlear implants, vascular clips, etc.), and cardiac pacemakers; 7.Poor compliance; participating in other research projects.

Design outcomes

Primary

MeasureTime frame
Resting state brain network;

Secondary

MeasureTime frame
IBS-SSS;Number of defecation per week;Bristol Fecal trait scale;HAMA;IBS-QOL;

Countries

China

Contacts

Public ContactYongkang Liu

The Affiliated Hospital of Nanjing University of Chinese Medicine

yongkangliu1987@163.com+86 18205081513

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026