Atrial fibrillation-associated ischemic stroke
Conditions
Interventions
AF+CE group:No
AF+LAA group:No
LAA group:No
AF group :No
Sponsors
The First Affiliated Hospital of Soochow University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria for stroke: 1. Aged >= 18 years; 2. Within 24 hours of onset, CTA+CTP indicates that the core of infarction exists or that the MRI examination time from the onset to the line of the skull is within 1 week, the MR DWI sequence can be seen as an acute cerebral infarction lesions; 3. Patients with initial onset or past cerebral infarction but no obvious sequelae, re-acute onset; 4. Patients completed ECG, Holter and electrostartic monitoring while in hospital. Inclusion criteria for the control group without stroke and atrial fibrillation: 1. Aged >= 18 years; 2. ECG or Holter and ECG monitoring indicate the presence of atrial fibrillation.
Exclusion criteria
Exclusion criteria: 1. Cerebral hemorrhage and occupied patients (emergency skull CT excludes cerebral hemorrhage, such as infarction after the patient's hospital incurs hemorrhage does not exclude); 2. Patients with transient ischemic attack; 3. Severe infection or Sepsis shock; 4. Patients with a history of severe trauma who have under been surgically treated;Obviously liver and renal failure; 5. Patients with endocrine, immune and tumor diseases; 6. During pregnancy; 7. Other causes of cardioembolic stroke, including patent foramen ovale, Left atrial myxoma, rheumatoid heart disease, dilated heart disease and hypertrophic cardiomyopathy; 8. There are other causes that can cause acute multiple infarction, such as vasculitis, clotting system diseases, tumor embolism, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gene Corin;Gene PCSK6;Serum level of NT-proBNP;Serum level of Corin protein; | — |
Countries
China
Contacts
Public ContactFang Qi
The First Affiliated Hospital of Soochow University
Outcome results
None listed