Thyroid Surgery
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ASA I-II, patients aged 18-65 years undergoing elective Thyroid surgery (including total thyroidectomy, subtotal thyroidectomy, radical thyroidectomy), Sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with diseases of the heart, brain, lung, liver, kidney and other major organs; 2. Allergic to ketamine, lidocaine and other drugs used in the experiment; 3. Recent use of ß-blockers; 4. Patients with hypertension, diabetes or hearing impairment; 5. Pregnant and lactating women, motion sickness; 6. Moderate or above anemia (hemoglobin < 90 g/L); 7. Alcoholics and drug abusers; 8. Long-term use of sedatives, analgesics, long-term alcoholics; 9. History of mental illness, language communication difficulties, unable to understand the experimental content; 10. Adverse drug reactions, such as allergic reactions, toxic reactions, etc.; 11. The surgical blood loss was more than 100 ml; 12. The scope of operation was changed, and thyroidectomy or cervical lymph node dissection was not performed. 13. The operation time was more than 90 min. 14. Difficult airway occurs during anesthesia induction, requiring to change the routine intubation method; 15. The patient refuses to continue the study during the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| QoR-40;SAS;SDS; | — |
Countries
China
Contacts
The Affiliated Huaian Hospital of Xuzhou Medical University, Huai'an Second Hospital