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Analysis of plantar pressure and its effect on related MMPs family proteins in patients with knee osteoarthritis treated by deep hyperthermia under traction

Analysis of plantar pressure and its effect on related MMPs family proteins in patients with knee osteoarthritis treated by deep hyperthermia under traction

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100043912
Enrollment
Unknown
Registered
2021-03-05
Start date
2017-01-01
Completion date
Unknown
Last updated
2021-07-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis of knee joint

Interventions

deep hyperthermia group:deep hyperthermia
control group:Knee joint massage, acupuncture and infrared therapy
Joint group:deep hyperthermia combined with traction

Sponsors

Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine, Hebei Province
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Imaging diagnosis was made by Khammerl grading method: Kellgren-Lawrence X-ray grading standard: 0 grade normal; grade I joint space suspected narrowing and osteophyte; grade II joint space suspected narrowing and obvious osteophyte; grade III joint space obviously narrowing, medium osteophyte, some bone hardening or wear; grade IV joint space obviously narrowing, a large number of osteophytes, severe bone sclerosis, obvious wear and deformity. 2. The included patients met the following conditions: knee joint pain, stiffness, swelling and other clinical symptoms were less than 5 months; the age was 50 - 65 years old; there was no joint operation in the past; informed consent was signed; KOA radiological evaluation was grade III / IV.

Exclusion criteria

Exclusion criteria: 1. Patients with severe cardiovascular and cerebrovascular diseases or organ failure unable to tolerate stimulation and mental patients; 2. Patients with abnormal gait due to neuromuscular factors (including stroke, brain trauma, spinal cord injury and disease, cerebral palsy, Parkinson's disease, etc.); 3. Patients with knee joint tumors, tuberculosis, infection, rheumatoid and other diseases; 4. Patients with diseases of spine, hip, ankle and foot that may affect gait measurement; 5. Patients older than 75 years old and less than 18 years old; 6. Patients who are unable to walk on their own because of joint pain and need to use other people or auxiliary tools to walk.

Design outcomes

Primary

MeasureTime frame
Lysholm knee score;MMPS protain;Interleukin-6;When the plantar regions begin to touch the ground;End of touchdown for all plantar regions;Stress Time ratio of different plantar regions;Volume of effusion in knee joint;

Countries

China

Contacts

Public ContactWang Li-chun
wanglichun1976@163.com+86 18031783966

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026