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Clinical study of clostridium butyricum MIYAIRI 588 regulating gut microbiota and immune status of tumor patients

Clinical study of clostridium butyricum MIYAIRI 588 regulating gut microbiota and immune status of tumor patients

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100043876
Enrollment
Unknown
Registered
2021-03-04
Start date
2021-02-19
Completion date
Unknown
Last updated
2021-07-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cancer

Interventions

1:Clostridium butyricum MIYAIRI588
2:none

Sponsors

The Tenth People' s Hospital, Medical School of Tongji University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Aged >= 18 years; 2. No gender limit; 3. Patients with malignant tumors undergoing non-surgical treatment; 4. The expected survival time is more than 3 months; 5. ECOG (Eastern Cooperative Oncology Group, ECOG) physical fitness score is 0~2; 6. Blood routine: HB >= 70g/L, ANC >= 1 x 10^9/L, PLT>=50 x 10^9/L; 7. Ability to sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients suffering from autoimmune diseases, or extremely low immunity, or accompanied by other diseases that require systemic use of immunosuppressive drugs or hormone therapy; 2. Human immunodeficiency virus (HIV) positive or active hepatitis B or C infection; 3. Patients with dysphagia or gastrointestinal obstruction; 4. Pregnant or lactating women; 5. Patients who have taken probiotics in the past three months or who have received fecal microbiota transplantation within six months.

Design outcomes

Primary

MeasureTime frame
Gut microbiome;

Secondary

MeasureTime frame
Immune status;Side effects of cancer treatment;

Countries

China

Contacts

Public ContactQin huanlong

The Tenth People's Hospital, Medical School of Tongji University

mixaoxueer@sina.com+86 21-66301161

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026