Sarcopenia
Conditions
Interventions
treatment group:resistance training
control group:Nutritional support, aerobic training, neuromuscular electrical stimulation
Sponsors
Shanghai Fourth Rehabilitation Hospital
Eligibility
Sex/Gender
All
Age
65 Years to 95 Years
Inclusion criteria
Inclusion criteria: Aged >= 65 years; basic communication skills; muscle manual testing >= grade 3; SARC-F scale score >= 4; voluntary participation in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: Acute changes in body composition, e.g. severe oedema, dehydration, etc.; unexplained fever or infection; patients who are unable to cooperate or have contraindications to body composition measurements, SPPB measurements, grip strength measurements, ultrasound diaphragm examinations, CT examinations; patients with acute heart failure, renal failure, respiratory failure and contraindications to rehabilitation training; patients with neurological, muscular or joint disorders that may affect lower limb exercise training or NMES; patients who have participated in rehabilitation training in the past 1 month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skeletal muscle mass index at the lumbar 3 vertebral level;Short physical performance battery;Grip strength;Body weight;Height;Waist circumference;Hip circumference;Neck circumference;Thigh circumference;Mid-thigh circumference;Skinfold thickness;Fat-free mass;Skeletal muscle mass;Fat area at the lumbar 3 vertebral level;Activity of daily living ability assessment;Waist-to-hip ratio;BMI;Serum albumin;Blood glucose;glycosylated hemoglobin;Blood lipid;25 hydroxyvitamin D;Body fat rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Calf circumference;Hamilton Depression Scale;Hamilton Anxiety Scale;St. George’S Respiratory Questionnaire;Borg scale;Modified Medical Research Council Dyspnea Scale;Peak expiratory flow;6 minutes walking distance;Thickness of diaphragm;Diaphragm mobility;Liver and renal function; | — |
Countries
China
Contacts
Public ContactYin Zhang
Shanghai Fourth Rehabilitation Hospital
Outcome results
None listed