Expression and mechanism of PI3Ks/RTK/MLCP induced pain and abnormal contraction of sarcomeres of myofascial trigger point

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100043853

Enrollment

Unknown

Registered

2021-03-04

Start date

2021-03-15

Completion date

Unknown

Last updated

2021-07-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Myofascial pain syndrome

Interventions

Intervention group:Biopsy at myofascial trigger point

Control group:Biopsy at myofascial trigger point

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Patients with shoulder and neck pain and hip pain are eligible for the diagnosis of myofascial pain syndrome: (1) palpable taut bands were found in the trapezius or gluteus medius muscles; (2) The presence of highly sensitive and localized induration in the tensor band; (3) pressing the induration can cause local pain and pain in distant parts; (4) Restricted range of motion of corresponding skeletal muscles. 2. Ages 18 to 70 years; 3. Sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Complicated with severe cardiovascular and cerebrovascular diseases; 2. Puncture site infection; 3. Coagulation dysfunction.

Design outcomes

Primary

Measure	Time frame
Expression of RTKs;Expression of MLCP;Expression of PI3K;	—

Secondary

Measure	Time frame
Visual analogue score of pain;	—

Countries

China

Contacts

Public ContactFeng Qi

Qilu Hospital of Shandong University

qifeng66321@sina.com+86 18560083756

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026