hypoxemia
Conditions
Interventions
0cmH2O PEEP:0cmH2O PEEP
5cmH2O PEEP:5cmH2O PEEP
The minimum driven pressure method was used to titrate individual PEEP group:The minimum driven pressure method was used to titrate individual PEEP
Optimal static lung compliance titration for individualized PEEP group:Optimal static lung compliance titration for individualized PEEP
Sponsors
The Second Affiliated Hospital of Harbin Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with elective abdominal tumor interventional therapy; ASA I ~ II; Age: 18-65 years old; BMI: 18 ~ 28 kg/m2; The patient and his family agreed and cooperated.
Exclusion criteria
Exclusion criteria: Severe respiratory diseases: including COPD, bullae, asthma, etc.; Complicated with serious cardiovascular diseases, such as congenital heart disease and coronary heart disease; Severe complications occurred during the operation, such as massive bleeding, anaphylactic shock, etc.Intraoperative SpO2 & lt; 90% for more than a minute.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The airway peak pressure;Airway platform pressure;Pulmonary dynamic compliance;Driving pressure;Arterial oxygen partial pressure;Arterial partial pressure of carbon dioxide;Differential oxygen pressure of alveolar artery;Oxygenation index;Intrapulmonary flux;Dead space fraction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart rate;Mean arterial pressure;Oxygen saturation of finger vein;CT scan of lung;Operation time;Pulmonary complications occurred five days after surgery;Hospitalization days; | — |
Countries
China
Contacts
Public ContactZhang Bing
Department of Anesthesiology, the Second Affiliated Hospital of Harbin Medical University
Outcome results
None listed