gastric and esophygeal tumors
Conditions
Interventions
Dex group:During the induction period of general anesthesia, dexmedetomidine with a concentration of 4 µ g / ml was administered intravenously at the rate of 1 µ g / kg for more than 10 minutes, follo
C ?:The same volume of saline with D group is administered during general anesthesia.
Sponsors
Beijing Friendship Hospital Affiliated to Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients aged 18-65 years, ASAI ~ II, scheduled for ESD surgery for gastric and esophageal tumors.
Exclusion criteria
Exclusion criteria: (1) Sinus bradycardia; (2) sick sinus syndrome; (3) predictable difficult airway or obesity (BMI > 35kg / cm2); (4) mental illness; (5) allergic to dexmedetomidine; (6) long-term history of opioid use; (7) refused follow-up or drug intervention after surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| visual analogue scales; | — |
Secondary
| Measure | Time frame |
|---|---|
| sedation score;postoperative nausea and vomiting(PONV) score;shivering score;satisfaction scores of patient at 48h;advert events;treatment and agents of posteoperative pain and rescue of adverse events; | — |
Countries
China
Contacts
Public ContactLixin An
Beijing Friendship Hospital affiliated to Capital Medical University
Outcome results
None listed