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Cross-sectional investigation of the characteristics of intestinal flora in patients with carotid atherosclerotic plaque ulcer

Cross-sectional investigation of the characteristics of intestinal flora in patients with carotid atherosclerotic plaque ulcer

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100043829
Enrollment
Unknown
Registered
2021-03-04
Start date
2021-03-04
Completion date
Unknown
Last updated
2021-07-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Carotid atherosclerotic plaque ulcer

Interventions

Sponsors

Dongzhimen Hospital of Beijing University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: Exposure group: Patients with carotid atherosclerotic plaque ulcer diagnosed by color Doppler ultrasound; The patients with lumen stenosis < 75% were selected; Subjects with at least one risk factor were hypertension or diabetes or hyperlipidemia. The subjects aged from 40 to 70 were not limited in gender; The patient informed consent and signed the informed consent form. Non exposure group: The patients with carotid atherosclerotic plaque but no ulcer were diagnosed by color Doppler ultrasound; Patients with lumen stenosis less than 75%; Subjects with at least one risk factor were hypertension or diabetes or hyperlipidemia. The subjects aged from 40 to 70 were not limited in gender; The patient informed consent and signed the informed consent form.

Exclusion criteria

Exclusion criteria: Exposure group: Patients with acute stroke or myocardial infarction in recent 3 months were excluded; Patients with severe arrhythmia, atrial fibrillation and heart failure were excluded; Patients with severe primary diseases such as liver, kidney, hematopoietic system, endocrine system and respiratory system were excluded; Patients with abnormal stool were excluded; Patients who were taking antibiotics were excluded; Pregnant women were excluded. Non exposure group: Patients with acute stroke or myocardial infarction in recent 3 months were excluded; Patients with severe primary diseases such as liver, kidney, hematopoietic system, endocrine system and respiratory system were excluded; Patients with abnormal stool were excluded; Patients who were taking antibiotics were excluded; Pregnant women were excluded.

Design outcomes

Primary

MeasureTime frame
Intestinal flora;Distribution characteristics of TCM syndrome elements;

Secondary

MeasureTime frame
Blood chemistry;Blood routine;

Countries

China

Contacts

Public ContactWu Shengxian

Dongzhimen Hospital of Beijing University of traditional Chinese Medicine

wushx@sina.com+86 13501382919

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026